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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a954b2fe4d41d7037f46d80f23066feb8a6915e31c1bae63cd4fc40fa720fcd1' 
  AND token = 'zX7rVx/YDyhwuaAWdLs9CD9MpmNrnTTOBxPWvXC+/kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}