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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b909d73635ced0ea1460f2b21eaa83bcb7b8138112b85a86485db34b6e0b853' 
  AND token = 'Hx6tqNkXqqJLco+4iqmZp6+0npr0Xp1EzrdWwlw1eSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}