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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e93c88f097f2a5d485e8a688133f8f2fa2f47280e90f9c9637c9d520d019dabb' 
  AND token = 'bURgreMiuU8px6j933OuVPKTToJm+nTXtcy+WXKbj9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}