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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0f3bbf07dc978e962fb6547a6928c81121b1f07e8f5f0f0c9831dc9057c21e' 
  AND token = 'BIQThmRONjKrEK6rpJxDyWKw9CP0u6+Ngd6D0Azd9EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}