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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed4008bc1d13fc9101499add552742d39834bf9ca9060b4e2b943740592864a' 
  AND token = 'CKuxU2owcoZvpT0qY/utZ84Yng5zxCyBIziwQNEMdU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}