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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fecc5491082e9a255822d8b196c5fe373259fdb1fcf5593657304b11e04b35b0' 
  AND token = 'mFNe51nj3dHPIdaFRWy+QLznme1AIYxeqLXXIdoZU0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}