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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cafa42b3a0bb1532cd64a412cdad184d83100d22e110650c1051752d9487b599' 
  AND token = 'aQNOIwkfKmPpZrWFXpm52YNiVmeuq4vKjpoZSbBDjPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}