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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71bc1c54296b9f99d16005900f1e4b3a924ddfd4bb23c88f126393fe0b54c265' 
  AND token = 'hi0OEa3ock3nGB+MhOfIGesNwTsv49auFCu2a4+dvTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}