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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a56ea789db598a84c73b8d92f538df94a2a0a816704fa68bbdb8edbb841862' 
  AND token = 'VfEYet96uozOp8tyMUFpDBbfkJbp5u5tYy+FFCmQmQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}