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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e933ea57ab6c257cf99cd140f3e685812f2695cff9c20f365331f6a94ae150' 
  AND token = 'Q7bzWY8FMs2W/OWcbvT4ZHehThfW40tUCuMyDQ66x3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}