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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9f08e516b3c9ba50d386baf93072f7d2957c76176ba41be782ed7407de5f75' 
  AND token = 'JoIKG4e3i8q8GwWCRDK31rNxXxhbbq4PPtcIRkUzoCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}