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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4b2d5f44eac85b12b7bac78a81edbffb386e14190ce791f66b54ff822062c73' 
  AND token = 'F+sN2kNgtmPtZp1xkJNMxSMzHZG1bUDmSdwj8lchThM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}