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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '570490ae0e2ab50d060a9b72376c0fcab6d665ea5d860eb919f4971b94d4601d' 
  AND token = 'Piv9ICGvySdYjfvJKb1T0mIAZqHegF9t+7CYRzG6U7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}