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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2179ebacc5d9cb60bb356d12e55e6ec95579ca3c1dc1e35811be2331df20adc' 
  AND token = 'UBIH6Mg0pIlm2j5PIC5fKgdY452uWPcsPUQb+2+/RDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}