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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ebd1e0feecba01ba69b74bb6aea0c5c7596495157f03b87a48e5bb626ed119' 
  AND token = 'XEwzfaiS7zXZJ99HdG7ZvkmlUd3qFuOtBsE9VmnEirs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}