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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e479328e70f2be5e1f39dde369e039ae784a3ccb4c3b584479caa7ac34d5abc6' 
  AND token = 'H5x6oMyZM3TeR5Hj2gqelRGOmqXlPAYDEte0xOV+tkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}