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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aafe9cd6bf912c3eb2d267a43e315e5257fe738e02ae540f3392a5af193e988' 
  AND token = '+CppxZlX6aRk5kL9xekfVRWnOw4WGKsoojvMDKZbKV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}