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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2959d5224a2641f181ea50b0a708169a70372ab1f725edae1b11ed67811a29b3' 
  AND token = '4b7643s0vAl1MC0i5b6gsxKIRpBHGuZkf4ImBK6mpyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}