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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3e8e12d5bdd84f6728b441cccdf26c1559550335180b09354c5dd85aa94bd0' 
  AND token = '4RC5GQoitfJoWHGGz2qUL3W6jt+MQWuoe8yXVvWsmSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}