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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c26d2c01bd3c1e8004f8fc9f8f0a17e21a83540071b404105a3c1c542c80932' 
  AND token = 'q5o5yEw/zdB2ezn1IhlEgw2JBPVey5tAWMZT2x8IKNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}