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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9424fbf32b165500ab8f53817ad6fb8b4098761ef0c3138008cb25b9c3e72833' 
  AND token = 'MCdNk6E5s/ydzQIInH8D7iVtweG5sm3c6c5aiLyKWeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}