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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0411684ed7f8403a9a99f95a17218a509555f0dfa7a124696ad8360d7a54d6' 
  AND token = 'cplv/E396+Y2Pc0QA9zqkDG3LAw+mQwLgA7dWIP8TCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}