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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ff46e906e64a18555da895bab48e1588f0ac8dd4f8296451b89a447f2c7f73' 
  AND token = 'ONho4VwDjz1xLpHboyQZE5Up5AOPD6pd8tQpi+aMl8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}