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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8e2e178dd65eb03aa3cfd1f28ed3c823a04964644133121c79989b571ba358' 
  AND token = 'zioswsXAFIWpDfmlj9BCAHzBWm5tafQocEgsUXJZF34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}