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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2767228efb51bb71b295e11209e346a5bd54512e06fa67aaaeaac8244c7ace0' 
  AND token = 'VKnsD4PscrN5Cwp3fDSD+tELG33AHSK/3aZn2ABF00M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}