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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6522af9741046114fa05c2de43d033f168e942ba62e4f8de4c485441c6380cc5' 
  AND token = 'S/Q1zyqeVw4KmPqWbr0hpfDgkbaHqf6izwmDb+r823s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}