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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd217aad3a86c521c82d03fb9025b8f328045dada58a15b8c3ccbbaa226e39d63' 
  AND token = 'f1KMWLSlJYsJX6HlUU4fv7Qnn2tEu0O/HLm7F67E0eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}