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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6d0a0765a37ccd31aabb66ff693e88d5f77e4f08e1054c25d75ff50a874c6a' 
  AND token = 'pq0K/AkFGXUO9a2b3cC06sp1cZbpuTXKxI9QnMxyPww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}