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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c144328529469a42087ea9cea09b5b64ead16ae90e659e862a0c27206b55c198' 
  AND token = '4YM+Gudxe6RCtQFWZ4N4yVTrI9ZbRjB9wMQWFkmwYRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}