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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3d090bb825e8a0a408844b54a45242c0d694416693de7842d049d39df4e4fd' 
  AND token = 'YtexS3xx6EMu9wgiC92PutO8l4fELMxtd34bdw3CDGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}