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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52eb9ec2d2cd21f5a35c303aea85ab693bb450aae45ddd07d6e14a00d1cba4a' 
  AND token = 'ML7Drpwz0/9713aiBZCI9vs+anGKXOZ4Uvt9U1eZ4U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}