SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb0da09c64b2d19d662430e75f9e2f7bbb91b4f288d850aed9535631590ab222' 
  AND token = 'DBLQ1PofTjPeBfbEJH/jdv+1P52YR7F2uHl9EmCklb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}