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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8190e11d6f99989fdab29b4b21043f60fb9ff38a41ab8023c4927db6ade198d' 
  AND token = 'ts46HMhWdrlwaRrqLUPW5S539hDxAVkxHfupLlf1LDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}