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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4160fb0a275d64b69802da2fa167b734ab281acf785a5b79ed4b8e7090f0e9a2' 
  AND token = 'FXA19dxMwI0y+LB1ZepyDO0kgOdktN7H76D6c+pyzFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}