SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff892433c6fceb71319cc671666721c9dbdb9bf4be1524d8f45adf2e3807175' 
  AND token = 'R9kCgWyzoJz0y2gfFsMS6zXGcQhrlnWH1bPSeMwe6Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}