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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39369ba493af19830db6bf97726efc04e4ef1203393cc08bc4d5a10938f9ba0' 
  AND token = 'CURM2AeI9D8ou43FzCdYSyjtERAKrITPyDkfyXArOTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}