SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdacacf06a00f31bf76654271e52569442b1f08df545f22aa30e6e2917bb1d97' 
  AND token = 'hkvTThBRuiWO+rSpb2M4nITGok64GXtIsG14cwp1kkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}