SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff036791883e4d863318fd452dce7c4ba31813e49810f7c0a09d09b32972feb' 
  AND token = 'MUgjq8fsfpT4k0tiTIyGLaNaaD+FK/h5gPCCu9Lqut0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}