SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d7473edd5247631d4e485e0c83a69d0d380057c3ca7b6258c200dc5d46419f' 
  AND token = 'RnLWHYsBHrTtBTsO+l2tokPWXJUBmtogiN+0y7aRJbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}