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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0259e4259fea223e338c3749a132091e6aa30ae1d010988724f7a23253f4ac5' 
  AND token = 'zjJP1IEivdc0H8vm4gYXeGjA/QW67jJW99JQPBJifPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}