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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0c4aaef34b8a26ca2c6fcbc28f929e118979d394fed26102da2bc6c1ffe44b' 
  AND token = 'QbnWFTJG2YzNKlvs1VRaFpcaBuv2LDHAwSnHRyNKWSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}