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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c80cb3b88c35fecc7c4a3cc5c2e4da52c7e4fa1563e0de1bb24e0e0e36ebf17' 
  AND token = 'xlwGJ+OsEEc+yFgsX97/LGu91S5Wwx8e9KGRi13B00U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}