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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad55ddc6aca8e68a24e556f2ec19489e7300efa8e889dc3ff960a3d67658f916' 
  AND token = 'ILp2DwfmY8DXnY5KC1Q+RoZWaNxmyODVj1Iu/yOsdLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}