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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46cc9d0da9682c6c3ed78d4898594ea2017468c39942664f22827212ba3c6a5' 
  AND token = 'uLICkD7kD/2L5Q//2f8+avLhTtkpXAIjZIbB5fkhxEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}