SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b5c4c8a200eae3685d91b5d58141af41486523b8796266e751dec6773d8ec4' 
  AND token = 'Bp/Qla1UNfUwD8t49Ss97uOqiCf9DcmOS+rK3A6/Brw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}