SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22f54d35411c2e9925d3ae1db4e4ca71dfce6b2327f2e2f122d7c97fbe30dd4' 
  AND token = 'VhktVZLvMpPaOPxBUhZM1JKXr5ot7y4l2koO3f1Llcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}