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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7455c1872163c0f835decaddc678628ad37ce074f1259390f8dfa69c34561c' 
  AND token = 'yxTNEYqOw/NEP+qT01FdAXBnvFCdYs9XND1RHADucBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}