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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfb62d9fe7b8deb7b25fd2d8841bfe69127d5690062b5d04e5b3da5a7fe4b086' 
  AND token = 'p/ziTxl5R+sGmspfv/UenZoqre/xRAbI1MSfBF+Xd4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}