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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6656911405f216b5d3f7f6545df69bc0c5509bf90a6d62cc0e8157d63b374c59' 
  AND token = 'q1QBai17S74u3t1bG+e4kyr7HqoX1eOtpoPexVETIBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}