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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736660205a07ad2e06929bf8185e207dad74f672f0c92dc126e22e795fedd8a5' 
  AND token = 'aN/++FLL0jCX9/14Tqzj4q2bpz6EY0Wxf7qWAAl4lGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}